Volume 3, Issue 6, November 2017, Page: 77-81
Drug Development for PCGF2 Protein, Involved in Formation of Human Breast Cancer by Polyphenols and Their Derivatives Extracted from Cowania maxicana
Jawaria Khan, Institute of Molecular Biology and Biotechnology, Bahaudin Zakariya University, Multan, Pakistan
Ardas Masood, Institute of Molecular Biology and Biotechnology, Bahaudin Zakariya University, Multan, Pakistan
Asma Noor, Institute of Molecular Biology and Biotechnology, Bahaudin Zakariya University, Multan, Pakistan
Muhammad Imran Qadir, Institute of Molecular Biology and Biotechnology, Bahaudin Zakariya University, Multan, Pakistan
Received: May 25, 2017;       Accepted: Oct. 8, 2017;       Published: Nov. 15, 2017
DOI: 10.11648/j.ijpc.20170306.12      View  1768      Downloads  100
Abstract
In women, the most commonly found cancer is breast cancer. PCGF2 (polycomb group RING finger protein 2) was found to be one of the reasons that cause breast carcinoma in women. Ring finger protein causes formation of multiprotein complexes and mediates interactions between different proteins. The polyphenols, extracted from Cowania maxicana and their derivatives were found to have anti proliferative activities. They showed greater efficiency and specificity towards the target protein PCGF2 (polycomb group RING finger protein 2).
Keywords
Breast Cancer, PCGF2, Polyphenols, Cowania maxicana, Pedunculagin
To cite this article
Jawaria Khan, Ardas Masood, Asma Noor, Muhammad Imran Qadir, Drug Development for PCGF2 Protein, Involved in Formation of Human Breast Cancer by Polyphenols and Their Derivatives Extracted from Cowania maxicana, International Journal of Pharmacy and Chemistry. Vol. 3, No. 6, 2017, pp. 77-81. doi: 10.11648/j.ijpc.20170306.12
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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