International Journal of Pharmacy and Chemistry

Volume 5, Issue 2, March 2019

  • Drug-Induced Liver Injury Predictions: Extended Clearance Model and Its Use for Prospective Transporter and Enzyme-Based Hepatic Cell Stress Grading

    Gian Camenisch

    Issue: Volume 5, Issue 2, March 2019
    Pages: 15-19
    Received: May 24, 2019
    Accepted: Jun. 27, 2019
    Published: Jul. 09, 2019
    Abstract: Many enzymes and transporters involved in the hepatic clearance of drugs also play an important role in endogenous compound transport. Inhibition of some of these active mechanisms has frequently been shown to be associated with Drug-Induced Liver Injury (DILI). The Extended Clearance Model (ECM) describes the complex interplay between the differen... Show More
  • Extraction Methods and Functional Properties of Protein from Arthospira platensis for Bioavailability of Algal Proteins

    Mahmood Mahali, Sibi G.

    Issue: Volume 5, Issue 2, March 2019
    Pages: 20-25
    Received: Aug. 13, 2019
    Accepted: Aug. 28, 2019
    Published: Sep. 11, 2019
    Abstract: Protein is one of the main nutrients that will be in short supply in the future. Alternative protein sources and production methods are required to fulfil the demand of protein requirements. Proteins from microalgae represent potential raw materials for the generation of protein based food ingredients. Arthospira platensis harbors high protein conc... Show More