International Journal of Pharmacy and Chemistry

Volume 7, Issue 2, March 2021

  • Evaluation of the Binding Property of Some Binders in Metronidazole Tablet Formulation

    Akodu Busayo Odunayo, Fasuba Ilesanmi Kayode, Akawa Ayodeji Benjamin, Adu Isaac Adekola, Olasehinde Oluwaseun Ruth

    Issue: Volume 7, Issue 2, March 2021
    Pages: 22-30
    Received: Feb. 17, 2021
    Accepted: Mar. 09, 2021
    Published: Mar. 30, 2021
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    Abstract: The binding property of five (5) commonly used binders in metronidazole granule and tablet formulations was studied. The binders studied included gelatin, polyvinylpyrrolidone (PVP), carboxymethylcellulose (CMC), maize starch and guar gum. The binders were incorporated as 5%w/w of tablet weight in each case. The granules were formulated by the wet ... Show More
  • Development and Validation of a UV/vis Spectrometric Method for Determination of Cefixim Trihydrate in Raw Materials (Pure) and Tablet Forms

    Mavanga Mabaya Timothy, Mankulu Kakumba Jocelyn, Mayangi Makola Mannix, Mbenza Puati Adelard, Mana Kialengila Didi, Mavar Tayey Mbay Jean, Mbinze Kindenge Jeremi

    Issue: Volume 7, Issue 2, March 2021
    Pages: 31-36
    Received: Mar. 13, 2021
    Accepted: Mar. 30, 2021
    Published: Apr. 13, 2021
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    Abstract: A Cefixim Trihydrate method was developed and validated for determination of Cefixim in raw materials and tablets. This was to enable quantification of the compound using an available and less expensive analytical method for those forms. Henceforth, this study aimed to develop and validate a fast, simple and economical Ultraviolet-visible (UV/vis) ... Show More