International Journal of Pharmacy and Chemistry

Volume 5, Issue 3, May 2019

  • Molecular Modelling Studies of Pyridazinone Derivatives as Antibutyrylcholinesterases

    Mehmet Abdullah Alagoz, Zeynep Ozdemir, Azime Berna Ozcelik

    Issue: Volume 5, Issue 3, May 2019
    Pages: 26-30
    Received: Jul. 30, 2019
    Accepted: Aug. 26, 2019
    Published: Sep. 16, 2019
    Abstract: Background: Butyrylcholinesterase (BChE) is known serine hydrolase enzymes responsible for the hydrolysis of acetylcholine (ACh). Although the role of the other serine hydrolase enzyme, acetylcholinesterase (AChE) in cholinergic transmission is well known, the role of BChE has not been elucidated sufficiently. The hydrolysis of acetylcholine in the... Show More
  • A Review on the Properties and Uses of Paracetamol

    Iwuozor Kingsley Ogemdi

    Issue: Volume 5, Issue 3, May 2019
    Pages: 31-35
    Received: Aug. 13, 2019
    Accepted: Sep. 06, 2019
    Published: Sep. 21, 2019
    Abstract: N-acylated aromatic amines (those having an acyl group, RCO- substituted on nitrogen) are important in over-the-counter headache remedies. Over-the-counter drugs are those you may buy without a prescription. Paracetamol is virtually the sole survivor of the so-called “aniline derivatives” or “aniline analgesics” which are; acetanilide, phenacetin a... Show More