International Journal of Pharmacy and Chemistry

Volume 7, Issue 5, September 2021

  • Evaluation of Tepi and Its Surrounding Coffee Collections Against Major Coffee Diseases at Gera and Tepi

    Gabisa Gidisa, Zenebe Wubshet, Negasa Dechasa

    Issue: Volume 7, Issue 5, September 2021
    Pages: 80-84
    Received: Aug. 06, 2021
    Accepted: Aug. 27, 2021
    Published: Sep. 13, 2021
    Abstract: Coffee has for centuries played an important role in the Ethiopian economy and represents the main cash crop cultivated by small-scale farmers for social, economic, political and ecological sustainability. The estimated coffee production area in Ethiopia is 561,761 ha. In Ethiopia, coffee berry disease (CBD), coffee wilt disease (CWD) and coffee le... Show More
  • Recent Progress in Preparation and Applications of Oxazino[4,3-a] pyrroloimidazo[5,4-f]benzimidazole (imino)quinone as an Anti-Cancer Agent

    Mohammed Yaqob Shareef, Noor Mohammed Yaqob Shareef

    Issue: Volume 7, Issue 5, September 2021
    Pages: 85-100
    Received: Apr. 14, 2021
    Accepted: Aug. 07, 2021
    Published: Sep. 15, 2021
    Abstract: The aim of this study is to prepare a novel precursor for the synthesis of imidazo[5,4- f]benzimidazole(imino)quinone. This will target the over-expression of the enzyme NAD(P)H: quinone oxidoreductase (NQO1) in solid tumours. An electron withdrawing group was incorporated into the structure, and the substituted ring size was reduced as this is hyp... Show More
  • Free Radical Scavenging Activity of a 70% Ethanol Extract of the Whole Herb of Platostoma africanum P. Beaur. (Lamiaceae)

    Oluwatoyin Alice Tella, Akawa Ayodeji Benjamin, Fasuba Ilesanmi Kayode, Adu Isaac Adekola, Akawa Oluwole Bidemi, Olaiya Oluranti Esther

    Issue: Volume 7, Issue 5, September 2021
    Pages: 101-110
    Received: Aug. 03, 2021
    Accepted: Aug. 20, 2021
    Published: Oct. 05, 2021
    Abstract: When oxidation by free radicals exceeds antioxidant systems in the body, oxidative stress usually results. This is common in the underlying processes leading to aging, infertility and of a range of non-communicable diseases including cancers, cardiovascular diseases, neurodegenerative diseases and rheumatoid arthritis. There exist measures to curb ... Show More